Biotin and derivatives
Apexbio Technology LLC DOTA-NHS-ESTER-25MG
DOTA-NHS-ester (CAS No 170908-81-3) is widely utilized in biomedical research primarily for its role as a bifunctional chelating agent used in radiolabeling and conjugation processes Originating from the conjugation of DOTA (a macrocyclic chelator) with N-hydroxysuccinimide (NHS) this compound facilitates the attachment of radioactive metals to biomolecules enhancing imaging and therapeutic applications It operates by forming stable complexes with metal ions targeting specific pathways for precise diagnostic or therapeutic delivery In vitro activities typically exhibit a nanomolar to low micromolar range making it suitable for various applications such as drug screening cell labeling and receptor targeting in oncology research Its use extends to both cell models and animal studies allowing for robust experimental analysis Experimental concentrations typically depend on the specific research design ensuring versatility across different scientific investigations
